Monday 29 February 2016

MUSCULAR TISSUE

*origin- mesoderm
*muscular tissue is about 30% of total tissue.
*total number of muscles in human body are 639
*muscular tissue also contain small amount of matrix.

Types of muscular tissue-

1. Skeletal muscular tissue.
2. Smooth muscular tissue.
3. Cardiac tissue.

1.Skeletal muscular tissue-

*shape-cylindrical and unbranched
*nucleus-it is multinucleated
*sarcolema-it represent plasma membrane of muscle fibre.
*sarcoplasm-it represent cytoplasmic content of muscle fibre.
*myoglobin-it is red in colour. it is Fe++ containing pigment,it carries oxygen
*dark band and I band are alternately arranged.
*found in hind and fore limbs.
*myofibril- about 1000 in number.

2.Smooth muscular tissue-

*shape-spindle fibre.
*sarcolemma-less developed or absent.
*sarcoplasm-present in very less amount.
*myofibril- very less in number.
*nucleus- single nucleate.
*complete absence on A-band and I- band.
*complete absence of myoglobulin.


3. Cardiac tissue

*shape-cylindrical and branched
*nucleus-multinucleate/ uninucleate.
*presence of well developed sarcolemma.
*presence of sarcoplasm.
*presence of myofibril in between 4 -1000
*alternately arranged A-band and I-band are present.
*presence of myoglobin.
*it is formed by fusion of two adjecent muscles fibre.
*it is found in heart.







FLUID CONNECTIVE TISSUE

*fluid connective tissue contain maximum amount of water and it doesn't contain fibrous matrix.
*Blood and Lymph are its example.

LYMPH

*it is colourless fluid contain WBC & Platelets and complete absence of RBC.

BLOOD - CELL  =  PLASMA
BLOOD - RBC  =LYMPH
PLASMA  - FIBRINOGEN PROTEIN  =  SERUM

*lymph also contain blood plasma protein but in less amount than blood.
*it stores fat and adipose tissue.
*it clots like blood.
*it circulate through lymphatic vessel.

BLOOD

*colour- bright red
*total volume- 6-7 Lt  [body wt/ 13 in adult]
*pH-7.4(arterial blood)
        7.3(venous blood)
*specific stain-Leishman stain
*components- liquid component -blood plasma
                       solid component-blood cell

BLOOD PLASMA

water

*85-92% of tatal volume of blood

albumin

*it is the smallest blood plasma protein
*it is about 4% of blood volume
*it maintain osmotic pressure of blood.
*decreased albumin causes -Oedema
increased albumin causes- Albuminaria

globulin

* it is of three types alpha (α), bita(β ), and gama(γ)
*first two helps in transportation of nutrients and the last one acts as immunoglobulin.

fibrinogen and prothrombin

*it helps in blood clotting

BLOOD CELL

RBC / ERYTHROCYTES

*size-7.5-8.5 micro meter in diameter in human
          largest RBC-Amphuma,79 micrometer.
          smallest RBC- Muskdeer, 4 micro meter.
*shape- biconcave in human
*nucleus-newly formed RBC has nucleus,but as their size increses, RBC looses their nucleus .
*life span-120 days in human
*site of formation-liver, spleen and bone marrow.
rate of formation-2-3 million /sec
*site of distruction-liver, bonemarrow and spleen, but mainly spleen.
*spleen is also called the graveyard of blood.
*RBC contain haemoglobin, hence it is red in colour.

WBC / LEUCOCYTE

*total count-4000-12000/cubic mm of body
*it nucleated colourless blood cell.
*life span-48 hours to 14 days.
*it is of two types-
  1. granulocyte-Basophil, Eosinophil and Neutrophil
  2. agranulocyte-Lymphocyte and Monocyte
*Basophil-it helps in secretion of heparin, histamine and serotonin chemicals.
*Eosinophil-it secretes antitoxic substance.
*Neutrophil-it helps in killing disease causing substance and paracite.
*Lymphocyte-it synthesise antibodies or immunoglobulin and provide immunity
*Monocyte-phagocytic in nature.

PLATELETS

*it is non-nucleated blood cell.
*it is the fragment of megakaryotic cell of bone marrow.
*function-helps in blood clotting
                 helps in repairing of damage of blood vessel.

THROMBOCYTES

*it is nucleated blood cell found in non-mammals
*it also helps in blood clotting.
*it help in repairing of blood vessel